Predicting variant deleteriousness in non-human species: applying the CADD approach in mouse

BACKGROUND: Predicting the deleteriousness of observed genomic variants has taken a step forward with the introduction of the Combined Annotation Dependent Depletion (CADD) approach, which trains a classifier on the wealth of available human genomic information. This raises the question whether it c...

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Detalles Bibliográficos
Autores principales: Groß, Christian, de Ridder, Dick, Reinders, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186050/
https://www.ncbi.nlm.nih.gov/pubmed/30314430
http://dx.doi.org/10.1186/s12859-018-2337-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186050/
https://www.ncbi.nlm.nih.gov/pubmed/30314430
http://dx.doi.org/10.1186/s12859-018-2337-5

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