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Dense neural networks for predicting chromatin conformation

BACKGROUND: DNA inside eukaryotic cells wraps around histones to form the 11nm chromatin fiber that can further fold into higher-order DNA loops, which may depend on the binding of architectural factors. Predicting how the DNA will fold given a distribution of bound factors, here viewed as a type of...

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Detalles Bibliográficos
Autores principales: Farré, Pau, Heurteau, Alexandre, Cuvier, Olivier, Emberly, Eldon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186068/
https://www.ncbi.nlm.nih.gov/pubmed/30314429
http://dx.doi.org/10.1186/s12859-018-2286-z