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Genetic polymorphism and natural selection of circumsporozoite surface protein in Plasmodium falciparum field isolates from Myanmar

BACKGROUND: Plasmodium falciparum circumsporozoite protein (PfCSP) is one of the most extensively studied malaria vaccine candidates, but the genetic polymorphism of PfCSP within and among the global P. falciparum population raises concerns regarding the efficacy of a PfCSP-based vaccine efficacy. I...

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Detalles Bibliográficos
Autores principales: Lê, Hương Giang, Kang, Jung-Mi, Moe, Mya, Jun, Hojong, Thái, Thị Lam, Lee, Jinyoung, Myint, Moe Kyaw, Lin, Khin, Sohn, Woon-Mok, Shin, Ho-Joon, Kim, Tong-Soo, Na, Byoung-Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186114/
https://www.ncbi.nlm.nih.gov/pubmed/30314440
http://dx.doi.org/10.1186/s12936-018-2513-0