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Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway

BACKGROUND: Andrographolide (Andro), a diterpenoid lactone, has been used for treatment of various cancers with less adverse effects. However, the underlying mechanisms regarding its anti-tumor mechanism still remain unclear. METHODS: Cell viability and proliferation were measured by CCK8 and CFSE d...

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Detalles Bibliográficos
Autores principales: Peng, Yulin, Wang, Yan, Tang, Ning, Sun, Dongdong, Lan, Yulong, Yu, Zhenlong, Zhao, Xinyu, Feng, Lei, Zhang, Baojing, Jin, Lingling, Yu, Fabiao, Ma, Xiaochi, Lv, Chuanzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186120/
https://www.ncbi.nlm.nih.gov/pubmed/30314513
http://dx.doi.org/10.1186/s13046-018-0926-9