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Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway
BACKGROUND: Andrographolide (Andro), a diterpenoid lactone, has been used for treatment of various cancers with less adverse effects. However, the underlying mechanisms regarding its anti-tumor mechanism still remain unclear. METHODS: Cell viability and proliferation were measured by CCK8 and CFSE d...
Autores principales: | Peng, Yulin, Wang, Yan, Tang, Ning, Sun, Dongdong, Lan, Yulong, Yu, Zhenlong, Zhao, Xinyu, Feng, Lei, Zhang, Baojing, Jin, Lingling, Yu, Fabiao, Ma, Xiaochi, Lv, Chuanzhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186120/ https://www.ncbi.nlm.nih.gov/pubmed/30314513 http://dx.doi.org/10.1186/s13046-018-0926-9 |
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