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Dynamic Optimization with Particle Swarms (DOPS): a meta-heuristic for parameter estimation in biochemical models

BACKGROUND: Mathematical modeling is a powerful tool to analyze, and ultimately design biochemical networks. However, the estimation of the parameters that appear in biochemical models is a significant challenge. Parameter estimation typically involves expensive function evaluations and noisy data,...

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Detalles Bibliográficos
Autores principales: Sagar, Adithya, LeCover, Rachel, Shoemaker, Christine, Varner, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186122/
https://www.ncbi.nlm.nih.gov/pubmed/30314484
http://dx.doi.org/10.1186/s12918-018-0610-x