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Murine DX5(+)NKT Cells Display Their Cytotoxic and Proapoptotic Potentials against Colitis-Inducing CD4(+)CD62L(high) T Cells through Fas Ligand

INTRODUCTION: It has been previously shown that immunoregulatory DX5(+)NKT cells are able to prevent colitis induced by CD4(+)CD62L(high) T lymphocytes in a SCID mouse model. The aim of this study was to further investigate the underlying mechanism in vitro. METHODS: CD4(+)CD62L(high) and DX5(+)NKT...

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Detalles Bibliográficos
Autores principales: Werner, Jens M., Damian, Michael, Farkas, Stefan A., Schlitt, Hans J., Geissler, Edward K., Hornung, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186349/
https://www.ncbi.nlm.nih.gov/pubmed/30364054
http://dx.doi.org/10.1155/2018/8175810