Cargando…

Murine DX5(+)NKT Cells Display Their Cytotoxic and Proapoptotic Potentials against Colitis-Inducing CD4(+)CD62L(high) T Cells through Fas Ligand

INTRODUCTION: It has been previously shown that immunoregulatory DX5(+)NKT cells are able to prevent colitis induced by CD4(+)CD62L(high) T lymphocytes in a SCID mouse model. The aim of this study was to further investigate the underlying mechanism in vitro. METHODS: CD4(+)CD62L(high) and DX5(+)NKT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Werner, Jens M., Damian, Michael, Farkas, Stefan A., Schlitt, Hans J., Geissler, Edward K., Hornung, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186349/ https://www.ncbi.nlm.nih.gov/pubmed/30364054 http://dx.doi.org/10.1155/2018/8175810

Ejemplares similares

DX5(+)NKT cells display phenotypical and functional differences between spleen and liver as well as NK1.1(-)Balb/c and NK1.1(+ )C57Bl/6 mice
por: Werner, Jens M, et al.
Publicado: (2011)

Pathogen-Induced Proapoptotic Phenotype and High CD95 (Fas) Expression Accompany a Suboptimal CD8(+) T-Cell Response: Reversal by Adenoviral Vaccine
por: Vasconcelos, José Ronnie, et al.
Publicado: (2012)

TCR/CD3 coupling to Fas-based cytotoxicity
Publicado: (1995)

iNKT Cells Suppress Pathogenic NK1.1(+)CD8(+) T Cells in DSS-Induced Colitis
por: Lee, Sung Won, et al.
Publicado: (2018)

Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection
por: Malyshkina, Anna, et al.
Publicado: (2017)

Invariant NKT cells facilitate cytotoxic T-cell activation via direct recognition of CD1d on T cells
por: Qin, Yingyu, et al.
Publicado: (2019)

Anaplasma phagocytophilum-Related Defects in CD8, NKT, and NK Lymphocyte Cytotoxicity
por: Scorpio, Diana G., et al.
Publicado: (2018)

CD70–CD27 ligation between neural stem cells and CD4(+) T cells induces Fas–FasL-mediated T-cell death
por: Lee, Eun Mi, et al.
Publicado: (2013)

Can we define CD3(+)CD56(+) cells as NKT cells with impunity?
por: Lenart, Marzena, et al.
Publicado: (2021)

CD8(+) T-cell immunity orchestrated by iNKT cells
por: Qin, Yingyu, et al.
Publicado: (2023)

Steroid Resistant CD8(+)CD28(null) NKT-Like Pro-inflammatory Cytotoxic Cells in Chronic Obstructive Pulmonary Disease
por: Hodge, Greg, et al.
Publicado: (2016)

Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity
por: Schneider, Pascal, et al.
Publicado: (1998)

The Function of CD3(+)CD56(+) NKT-Like Cells in HIV-Infected Individuals
por: Jiang, Yongjun, et al.
Publicado: (2014)

EBV Promotes Human CD8(+) NKT Cell Development
por: Yuling, He, et al.
Publicado: (2010)

Contribution of Leishmania braziliensis antigen-specific CD4(+) T, CD8(+) T, NK and CD3(+)CD56(+)NKT cells in the immunopathogenesis of cutaneous leishmaniasis patients: Cytotoxic, activation and exhaustion profiles
por: Cunha, Clarissa F., et al.
Publicado: (2020)

Opposing Roles of DCs and iNKT Cells in the Induction of Foxp3 Expression by MLN CD25(+)CD4(+) T Cells during IFNγ-Driven Colitis
por: Lee, Sung Won, et al.
Publicado: (2022)

IL-7 During Antigenic Stimulation Using Allogeneic Dendritic Cells Promotes Expansion of CD45RA(-)CD62L(+)CD4(+) Invariant NKT Cells With Th-2 Biased Cytokine Production Profile
por: Trujillo-Ocampo, Abel, et al.
Publicado: (2020)

Fas receptor (CD95) & Fas ligand (CD178) expression in patients with tobacco-related intraoral squamous cell carcinoma
por: Das, Satya N., et al.
Publicado: (2011)

CD3(+)CD4(neg)CD8(neg) (double negative) T lymphocytes and NKT cells as the main cytotoxic-related-CD107a(+) cells in lesions of cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis
por: Ferraz, Raquel, et al.
Publicado: (2017)

Antitumor Immunity Produced by the Liver Kupffer Cells, NK Cells, NKT Cells, and CD8(+) CD122(+) T Cells
por: Seki, Shuhji, et al.
Publicado: (2011)

Mouse CD8(+)NKT-like cells exert dual cytotoxicity against mouse tumor cells and myeloid-derived suppressor cells
por: Li, Zhengyuan, et al.
Publicado: (2019)

Corrigendum: IL-7 During Antigenic Stimulation Using Allogeneic Dendritic Cells Promotes Expansion of CD45RA(-)CD62L(+)CD4(+) Invariant NKT Cells With Th-2 Biased Cytokine Production Profile
por: Trujillo-Ocampo, Abel, et al.
Publicado: (2021)

Soluble HLA Class I Molecules/CD8 Ligation Trigger Apoptosis of CD8 Cells by Fas/Fas-Ligand Interaction
por: Puppo, Francesco, et al.
Publicado: (2002)

Type II NKT cells differentially regulate CD4 T cell subsets
por: Robertson, Faith C, et al.
Publicado: (2014)

CD1d-dependent Activation of NKT Cells Aggravates Atherosclerosis
por: Tupin, Emmanuel, et al.
Publicado: (2004)

Retraction: EBV Promotes Human CD8(+) NKT Cell Development
por: Yuling, He, et al.
Publicado: (2010)

Formation of DX-centers in indium doped CdTe
por: Türker, M, et al.
Publicado: (2008)

Dysfunction of circulating CD3(+)CD56(+) NKT-like cells in type 2 diabetes mellitus
por: Tang, Ling, et al.
Publicado: (2023)

A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand- induced apoptosis
Publicado: (1996)

CD95/Fas ligand mRNA is toxic to cells
por: Putzbach, Will, et al.
Publicado: (2018)

The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation
por: McCarthy, Corinna, et al.
Publicado: (2007)

Proapoptotic genes BAX and CD40L are predictors of survival in transitional cell carcinoma of the bladder
por: Hussain, S A, et al.
Publicado: (2003)

Altered phenotypic and functional characteristics of CD3(+)CD56(+) NKT-like cells in human gastric cancer
por: Peng, Liu-sheng, et al.
Publicado: (2016)

Baseline CD3+CD56+ (NKT-like) Cells and the Outcome of Influenza Vaccination in Children Undergoing Chemotherapy
por: Leibinger, Evelin A., et al.
Publicado: (2021)

CD1d Expression and Invariant NKT Cell Responses in Herpesvirus Infections
por: Chung, Brian K., et al.
Publicado: (2015)

A distinct CD38(+)CD45RA(+) population of CD4(+), CD8(+), and double-negative T cells is controlled by FAS
por: Maccari, Maria Elena, et al.
Publicado: (2020)

Decreased effector memory CD45RA(+ )CD62L(- )CD8(+ )T cells and increased central memory CD45RA(- )CD62L(+ )CD8(+ )T cells in peripheral blood of rheumatoid arthritis patients
por: Maldonado, Anastacia, et al.
Publicado: (2003)

Constitutive CD8 expression drives innate CD8(+) T-cell differentiation via induction of iNKT2 cells
por: Kojo, Satoshi, et al.
Publicado: (2020)

Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening
por: Voss, Matthias, et al.
Publicado: (2009)

CD95/Fas promotes tumour growth
por: Chen, Lina, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_4t81mdvmq4gv7l7avhcs0cr2r3