Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis

We determined the roles of TLR3 and TLR9 in adverse events of polymicrobial sepsis, with a focus on development of septic cardiomyopathy, progression of which we have recently shown to be complement- and histones-dependent. So Wt, TLR3-knocked out (K.O.), and TLR9-K.O. mice were subjected to polymic...

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Detalles Bibliográficos
Autores principales: Fattahi, Fatemeh, Russell, Mark W., Malan, Elizabeth A., Parlett, Michella, Abe, Elizabeth, Zetoune, Firas S., Ward, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186377/
https://www.ncbi.nlm.nih.gov/pubmed/30364002
http://dx.doi.org/10.1155/2018/4302726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186377/
https://www.ncbi.nlm.nih.gov/pubmed/30364002
http://dx.doi.org/10.1155/2018/4302726

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