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Effects of rheumatoid arthritis associated transcriptional changes on osteoclast differentiation network in the synovium

BACKGROUND: Osteoclast differentiation in the inflamed synovium of rheumatoid arthritis (RA) affected joints leads to the formation of bone lesions. Reconstruction and analysis of protein interaction networks underlying specific disease phenotypes are essential for designing therapeutic intervention...

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Detalles Bibliográficos
Autores principales: Harshan, Shilpa, Dey, Poulami, Ragunathan, Srivatsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186409/
https://www.ncbi.nlm.nih.gov/pubmed/30324023
http://dx.doi.org/10.7717/peerj.5743