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Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients

BACKGROUND: Neuroblastoma is characterized by substantial clinical heterogeneity. Despite intensive treatment, the survival rates of high-risk neuroblastoma patients are still disappointingly low. Somatic chromosomal copy number aberrations have been shown to be associated with patient outcome, part...

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Detalles Bibliográficos
Autores principales: Depuydt, Pauline, Boeva, Valentina, Hocking, Toby D, Cannoodt, Robrecht, Ambros, Inge M, Ambros, Peter F, Asgharzadeh, Shahab, Attiyeh, Edward F, Combaret, Valérie, Defferrari, Raffaella, Fischer, Matthias, Hero, Barbara, Hogarty, Michael D, Irwin, Meredith S, Koster, Jan, Kreissman, Susan, Ladenstein, Ruth, Lapouble, Eve, Laureys, Geneviève, London, Wendy B, Mazzocco, Katia, Nakagawara, Akira, Noguera, Rosa, Ohira, Miki, Park, Julie R, Pötschger, Ulrike, Theissen, Jessica, Tonini, Gian Paolo, Valteau-Couanet, Dominique, Varesio, Luigi, Versteeg, Rogier, Speleman, Frank, Maris, John M, Schleiermacher, Gudrun, De Preter, Katleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186524/
https://www.ncbi.nlm.nih.gov/pubmed/29514301
http://dx.doi.org/10.1093/jnci/djy022