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Immediate release tablet formulation of varenicline salicylate and comparative pharmacokinetic study in human volunteers
PURPOSE: To develop an immediate release-type tablet containing varenicline salicylate (VRC-S), a smoking cessation agent, formulation and stability studies were performed. The in vitro dissolution and in vivo pharmacokinetic (PK) behavior of the tablets were compared with those of the commercial pr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186768/ https://www.ncbi.nlm.nih.gov/pubmed/30349192 http://dx.doi.org/10.2147/DDDT.S178456 |