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Clinical PET Imaging of Microglial Activation: Implications for Microglial Therapeutics in Alzheimer’s Disease

In addition to extracellular β-amyloid plaques and intracellular neurofibrillary tangles, neuroinflammation has been identified as a key pathological characteristic of Alzheimer’s disease (AD). Once activated, neuroinflammatory cells called microglia acquire different activation phenotypes. At the e...

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Detalles Bibliográficos
Autores principales: Shen, Zhiwei, Bao, Xinjie, Wang, Renzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186779/
https://www.ncbi.nlm.nih.gov/pubmed/30349474
http://dx.doi.org/10.3389/fnagi.2018.00314