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Discovery of Bacterial Deaminases That Convert 5-Fluoroisocytosine Into 5-Fluorouracil

Cytosine is one of the four letters of a standard genetic code, found both in DNA and in RNA. This heterocyclic base can be converted into uracil upon the action of the well-known cytosine deaminase. Isocytosine (2-aminouracil) is an isomer of cytosine, yet the enzymes that could convert it into ura...

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Detalles Bibliográficos
Autores principales: Aučynaitė, Agota, Rutkienė, Rasa, Tauraitė, Daiva, Meškys, Rolandas, Urbonavičius, Jaunius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186785/
https://www.ncbi.nlm.nih.gov/pubmed/30349513
http://dx.doi.org/10.3389/fmicb.2018.02375