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Inhibition of Autophagy in Microglia Alters Depressive-Like Behavior via BDNF Pathway in Postpartum Depression

Postpartum depression (PPD) is associated with mood disorders and elevated inflammation. Studies have evidenced the activation/inhibition of autophagy and excessive activation of microglia to have a close relationship with depression. C57 and microglia-specific autophagy-deficient mice (Cx3Cr1(Cre/+...

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Detalles Bibliográficos
Autores principales: Tan, Xiaoning, Du, Xiaoxue, Jiang, Yuting, Botchway, Benson O. A., Hu, Zhiying, Fang, Marong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186788/
https://www.ncbi.nlm.nih.gov/pubmed/30349488
http://dx.doi.org/10.3389/fpsyt.2018.00434