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Rapamycin Nano-Micelle Ophthalmic Solution Reduces Corneal Allograft Rejection by Potentiating Myeloid-Derived Suppressor Cells' Function

Allograft rejection is the major cause of corneal allograft failure. Rapamycin (RAPA) has been reported as an effective and novel immunosuppressive agent for patients undergoing corneal transplantation. However, its high water insolubility and low bioavailability have strongly constrained its clinic...

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Detalles Bibliográficos
Autores principales: Wei, Chao, Wang, Yuexin, Ma, Li, Wang, Xin, Chi, Hao, Zhang, Sai, Liu, Ting, Li, Zhiyuan, Xiang, Demeng, Dong, Yanling, Wu, Xianggen, Shi, Weiyun, Gao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186809/
https://www.ncbi.nlm.nih.gov/pubmed/30349533
http://dx.doi.org/10.3389/fimmu.2018.02283