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BAFF and BAFF-Receptor in B Cell Selection and Survival

The BAFF-receptor (BAFFR) is encoded by the TNFRSF13C gene and is one of the main pro-survival receptors in B cells. Its function is impressively documented in humans by a homozygous deletion within exon 2, which leads to an almost complete block of B cell development at the stage of immature/transi...

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Detalles Bibliográficos
Autores principales: Smulski, Cristian R., Eibel, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186824/
https://www.ncbi.nlm.nih.gov/pubmed/30349534
http://dx.doi.org/10.3389/fimmu.2018.02285