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Identification of the Acinetobacter baumannii Ribonuclease P Catalytic Subunit: Cleavage of a Target mRNA in the Presence of an External Guide Sequence

The bacterial ribonuclease P or RNase P holoenzyme is usually composed of a catalytic RNA subunit, M1, and a cofactor protein, C5. This enzyme was first identified for its role in maturation of tRNAs by endonucleolytic cleavage of the pre-tRNA. The RNase P endonucleolytic activity is characterized b...

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Detalles Bibliográficos
Autores principales: Davies-Sala, Carol, Jani, Saumya, Zorreguieta, Angeles, Tolmasky, Marcelo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186949/
https://www.ncbi.nlm.nih.gov/pubmed/30349524
http://dx.doi.org/10.3389/fmicb.2018.02408