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Andrographolide Prevents EV-D68 Replication by Inhibiting the Acidification of Virus-Containing Endocytic Vesicles

Enterovirus D68 (EV-D68) has emerged as a significant respiratory pathogen that can cause severe respiratory disease and acute neurologic disease. At present, there are no approved antiviral agents or vaccines for EV-D68. In this study, we demonstrate that andrographolide (ADO), an active component...

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Detalles Bibliográficos
Autores principales: Wang, Dongyin, Guo, Haoran, Chang, Junliang, Wang, Dong, Liu, Bin, Gao, Pujun, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186950/
https://www.ncbi.nlm.nih.gov/pubmed/30349523
http://dx.doi.org/10.3389/fmicb.2018.02407