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Korean Red Ginseng extract and ginsenoside Rg3 have anti-pruritic effects on chloroquine-induced itch by inhibition of MrgprA3/TRPA1-mediated pathway

BACKGROUND: It was previously found that Korean Red Ginseng water extract (KRGE) inhibits the histamine-induced itch signaling pathway in peripheral sensory neurons. Thus, in the present study, we investigated whether KRGE inhibited another distinctive itch pathway induced by chloroquine (CQ); a rep...

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Detalles Bibliográficos
Autores principales: Lee, Wook-Joo, Kim, Young-Sik, Shim, Won-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187082/
https://www.ncbi.nlm.nih.gov/pubmed/30337807
http://dx.doi.org/10.1016/j.jgr.2017.05.004