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Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) results from mutations in the gene encoding dystrophin which lead to impaired function of skeletal and cardiac muscle, but little is known about the effects of the disease on vascular smooth muscle cells (SMCs). Here we used the mdx mouse model to study the effects...

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Detalles Bibliográficos
Autores principales: Pritchard, Harry A. T., Pires, Paulo W., Yamasaki, Evan, Thakore, Pratish, Earley, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187127/
https://www.ncbi.nlm.nih.gov/pubmed/30181262
http://dx.doi.org/10.1073/pnas.1804593115