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Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis

Nuclear hormone receptors (NRs), such as retinoic acid receptors (RARs), play critical roles in vertebrate development and homeostasis by regulating target gene transcription. Their activity is controlled by ligand-dependent release of corepressors and subsequent recruitment of coactivators, but how...

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Detalles Bibliográficos
Autores principales: Hong, Suk-Hyun, Fang, Sungsoon, Lu, Benson C., Nofsinger, Russell, Kawakami, Yasuhiko, Castro, Glenda L., Yin, Yunqiang, Lin, Chengqi, Yu, Ruth T., Downes, Michael, Izpisúa Belmonte, Juan Carlos, Shilatifard, Ali, Evans, Ronald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187131/
https://www.ncbi.nlm.nih.gov/pubmed/30254164
http://dx.doi.org/10.1073/pnas.1809480115