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Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis
Nuclear hormone receptors (NRs), such as retinoic acid receptors (RARs), play critical roles in vertebrate development and homeostasis by regulating target gene transcription. Their activity is controlled by ligand-dependent release of corepressors and subsequent recruitment of coactivators, but how...
Autores principales: | Hong, Suk-Hyun, Fang, Sungsoon, Lu, Benson C., Nofsinger, Russell, Kawakami, Yasuhiko, Castro, Glenda L., Yin, Yunqiang, Lin, Chengqi, Yu, Ruth T., Downes, Michael, Izpisúa Belmonte, Juan Carlos, Shilatifard, Ali, Evans, Ronald M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187131/ https://www.ncbi.nlm.nih.gov/pubmed/30254164 http://dx.doi.org/10.1073/pnas.1809480115 |
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