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Mechanics of mouse blastocyst hatching revealed by a hydrogel-based microdeformation assay

Mammalian embryos are surrounded by an acellular shell, the zona pellucida. Hatching out of the zona is crucial for implantation and continued development of the embryo. Clinically, problems in hatching can contribute to failure in assisted reproductive intervention. Although hatching is fundamental...

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Detalles Bibliográficos
Autores principales: Leonavicius, Karolis, Royer, Christophe, Preece, Chris, Davies, Benjamin, Biggins, John S., Srinivas, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187134/
https://www.ncbi.nlm.nih.gov/pubmed/30232257
http://dx.doi.org/10.1073/pnas.1719930115