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Mechanics of mouse blastocyst hatching revealed by a hydrogel-based microdeformation assay
Mammalian embryos are surrounded by an acellular shell, the zona pellucida. Hatching out of the zona is crucial for implantation and continued development of the embryo. Clinically, problems in hatching can contribute to failure in assisted reproductive intervention. Although hatching is fundamental...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187134/ https://www.ncbi.nlm.nih.gov/pubmed/30232257 http://dx.doi.org/10.1073/pnas.1719930115 |