Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle

Nebulin is a giant sarcomeric protein that spans along the actin filament in skeletal muscle, from the Z-disk to near the thin filament pointed end. Mutations in nebulin cause muscle weakness in nemaline myopathy patients, suggesting that nebulin plays important roles in force generation, yet little...

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Detalles Bibliográficos
Autores principales: Kiss, Balázs, Lee, Eun-Jeong, Ma, Weikang, Li, Frank W., Tonino, Paola, Mijailovich, Srboljub M., Irving, Thomas C., Granzier, Henk L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187167/
https://www.ncbi.nlm.nih.gov/pubmed/30249654
http://dx.doi.org/10.1073/pnas.1804726115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187167/
https://www.ncbi.nlm.nih.gov/pubmed/30249654
http://dx.doi.org/10.1073/pnas.1804726115

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