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Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle

Nebulin is a giant sarcomeric protein that spans along the actin filament in skeletal muscle, from the Z-disk to near the thin filament pointed end. Mutations in nebulin cause muscle weakness in nemaline myopathy patients, suggesting that nebulin plays important roles in force generation, yet little...

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Detalles Bibliográficos
Autores principales:	Kiss, Balázs, Lee, Eun-Jeong, Ma, Weikang, Li, Frank W., Tonino, Paola, Mijailovich, Srboljub M., Irving, Thomas C., Granzier, Henk L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187167/ https://www.ncbi.nlm.nih.gov/pubmed/30249654 http://dx.doi.org/10.1073/pnas.1804726115

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