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The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia

Alzheimer's dementia commonly impacts the health of older adults and lacks any preventative therapy. While Alzheimer's dementia risk has a substantial genetic component, the specific molecular mechanisms and neuropathologies triggered by most of the known genetic variants are unclear. Resu...

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Detalles Bibliográficos
Autores principales: Tasaki, Shinya, Gaiteri, Chris, Mostafavi, Sara, De Jager, Philip L., Bennett, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187226/
https://www.ncbi.nlm.nih.gov/pubmed/30349450
http://dx.doi.org/10.3389/fnins.2018.00699