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A Horizontal Magnetic Tweezers and Its Use for Studying Single DNA Molecules

We report the development of a magnetic tweezers that can be used to micromanipulate single DNA molecules by applying picoNewton (pN)-scale forces in the horizontal plane. The resulting force–extension data from our experiments show high-resolution detection of changes in the DNA tether’s extension:...

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Detalles Bibliográficos
Autores principales: Fabian, Roberto, Tyson, Christopher, Tuma, Pamela L., Pegg, Ian, Sarkar, Abhijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187538/
https://www.ncbi.nlm.nih.gov/pubmed/30424121
http://dx.doi.org/10.3390/mi9040188