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Estimation of Trait-Model Parameters in a MOD Score Linkage Analysis

BACKGROUND/AIMS: Theoretically, the trait-model parameters (disease allele frequency and penetrance function) can be estimated without bias in a MOD score linkage analysis. We aimed to practically evaluate the MOD score approach regarding its ability to provide unbiased trait-model parameters for va...

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Detalles Bibliográficos
Autores principales: Brugger, Markus, Rospleszcz, Susanne, Strauch, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187844/
https://www.ncbi.nlm.nih.gov/pubmed/29131067
http://dx.doi.org/10.1159/000479738