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Estimation of Trait-Model Parameters in a MOD Score Linkage Analysis
BACKGROUND/AIMS: Theoretically, the trait-model parameters (disease allele frequency and penetrance function) can be estimated without bias in a MOD score linkage analysis. We aimed to practically evaluate the MOD score approach regarding its ability to provide unbiased trait-model parameters for va...
Autores principales: | Brugger, Markus, Rospleszcz, Susanne, Strauch, Konstantin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187844/ https://www.ncbi.nlm.nih.gov/pubmed/29131067 http://dx.doi.org/10.1159/000479738 |
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