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Sulforaphane inhibits growth and blocks Wnt/β-catenin signaling of colorectal cancer cells

The naturally occurring isothiocyanate sulforaphane (SFN) from cruciferous vegetables is associated with growth inhibition of various cancer types, including colorectal cancer. Colorectal cancer is most frequently driven by hyperactive Wnt/β-catenin signaling. Here, we show that SFN treatment reduce...

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Detalles Bibliográficos
Autores principales: Bernkopf, Dominic B., Daum, Gabriele, Brückner, Martina, Behrens, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188060/
https://www.ncbi.nlm.nih.gov/pubmed/30338040
http://dx.doi.org/10.18632/oncotarget.26125