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Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition

IS607-family transposons are unusual because they do not have terminal inverted repeats or generate target site duplications. They encode two protein-coding genes, but only tnpA is required for transposition. Our X-ray structures confirm that TnpA is a member of the serine recombinase (SR) family, b...

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Detalles Bibliográficos
Autores principales: Chen, Wenyang, Mandali, Sridhar, Hancock, Stephen P, Kumar, Pramod, Collazo, Michael, Cascio, Duilio, Johnson, Reid C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188088/
https://www.ncbi.nlm.nih.gov/pubmed/30289389
http://dx.doi.org/10.7554/eLife.39611