The effect of intravenous hydration strategy on plasma methotrexate clearance during intravenous high-dose methotrexate administration in pediatric oncology patients

BACKGROUND: High-dose methotrexate (HD-MTX) is widely used as a standard chemotherapeutic agent in pediatric cancers. Most research studies have confirmed the therapeutic efficacy of HD-MTX; however, strategies to prevent side effects vary among institutions, especially in developing countries, with...

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Detalles Bibliográficos
Autores principales: Traivaree, Chanchai, Likasitthananon, Napakjira, Monsereenusorn, Chalinee, Rujkijyanont, Piya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188117/
https://www.ncbi.nlm.nih.gov/pubmed/30349379
http://dx.doi.org/10.2147/CMAR.S172117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188117/
https://www.ncbi.nlm.nih.gov/pubmed/30349379
http://dx.doi.org/10.2147/CMAR.S172117

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