Oncogenic driver FGFR3-TACC3 is dependent on membrane trafficking and ERK signaling

Fusion proteins resulting from chromosomal translocations have been identified as oncogenic drivers in many cancers, allowing them to serve as potential drug targets in clinical practice. The genes encoding FGFRs, Fibroblast Growth Factor Receptors, are commonly involved in such translocations, with...

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Detalles Bibliográficos
Autores principales: Nelson, Katelyn N., Meyer, April N., Wang, Clark G., Donoghue, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188140/
https://www.ncbi.nlm.nih.gov/pubmed/30344944
http://dx.doi.org/10.18632/oncotarget.26142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188140/
https://www.ncbi.nlm.nih.gov/pubmed/30344944
http://dx.doi.org/10.18632/oncotarget.26142

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