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Oncogenic driver FGFR3-TACC3 is dependent on membrane trafficking and ERK signaling
Fusion proteins resulting from chromosomal translocations have been identified as oncogenic drivers in many cancers, allowing them to serve as potential drug targets in clinical practice. The genes encoding FGFRs, Fibroblast Growth Factor Receptors, are commonly involved in such translocations, with...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188140/ https://www.ncbi.nlm.nih.gov/pubmed/30344944 http://dx.doi.org/10.18632/oncotarget.26142 |