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Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach

It is well known that activating mutations in the KRAS and NRAS genes are associated with poor response to anti-EGFR therapies in patients with metastatic colorectal cancer (mCRC). Approximately half of the patients with wild-type (WT) KRAS colorectal carcinoma do not respond to these therapies. Thi...

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Detalles Bibliográficos
Autores principales:	del Carmen, Sofía, Sayagués, José María, Bengoechea, Oscar, Anduaga, María Fernanda, Alcazar, Jose Antonio, Gervas, Ruth, García, Jacinto, Orfao, Alberto, Bellvis, Luis Muñoz, Sarasquete, María Eugenia, del Mar Abad, María
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188146/ https://www.ncbi.nlm.nih.gov/pubmed/30344942 http://dx.doi.org/10.18632/oncotarget.26081

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