SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis

BACKGROUND: Increasing evidence suggests that SALL4 plays oncogenic roles in cancer development and progression. We have previously shown that SALL4 is highly expressed in gastric cancer, and its upregulation is associated with lymph node metastasis and poor prognosis. The role of SALL4 in gastric c...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Zhang, Peng, Shao, Meng, Zang, Xueyan, Zhang, Jiayin, Mao, Fei, Qian, Hui, Xu, Wenrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188178/
https://www.ncbi.nlm.nih.gov/pubmed/30349378
http://dx.doi.org/10.2147/CMAR.S177373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188178/
https://www.ncbi.nlm.nih.gov/pubmed/30349378
http://dx.doi.org/10.2147/CMAR.S177373

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