Peptide dendrimers as “lead compounds” for the treatment of chronic lung infections by Pseudomonas aeruginosa in cystic fibrosis patients: in vitro and in vivo studies

AIM: In the present work, the potential of the D-enantiomeric dendrimers dG3KL and dTNS18 was evaluated in relation to tobramycin (Tob), for the development of novel antibacterials to treat Pseudomonas aeruginosa chronic lung infections in patients with cystic fibrosis. RESULTS: The activity of dend...

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Detalles Bibliográficos
Autores principales: Pompilio, Arianna, Geminiani, Cristina, Mantini, Paolo, Siriwardena, Thissa N, Di Bonaventura, Ivan, Reymond, Jean Louis, Di Bonaventura, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188189/
https://www.ncbi.nlm.nih.gov/pubmed/30349334
http://dx.doi.org/10.2147/IDR.S168868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188189/
https://www.ncbi.nlm.nih.gov/pubmed/30349334
http://dx.doi.org/10.2147/IDR.S168868

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