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Peptide dendrimers as “lead compounds” for the treatment of chronic lung infections by Pseudomonas aeruginosa in cystic fibrosis patients: in vitro and in vivo studies
AIM: In the present work, the potential of the D-enantiomeric dendrimers dG3KL and dTNS18 was evaluated in relation to tobramycin (Tob), for the development of novel antibacterials to treat Pseudomonas aeruginosa chronic lung infections in patients with cystic fibrosis. RESULTS: The activity of dend...
Autores principales: | Pompilio, Arianna, Geminiani, Cristina, Mantini, Paolo, Siriwardena, Thissa N, Di Bonaventura, Ivan, Reymond, Jean Louis, Di Bonaventura, Giovanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188189/ https://www.ncbi.nlm.nih.gov/pubmed/30349334 http://dx.doi.org/10.2147/IDR.S168868 |
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