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Antioxidant modifications induced by the new metformin derivative HL156A regulate metabolic reprogramming in SAMP1/kl (-/-) mice

Aging is characterized by a reduced ability to defend against stress, an inability to maintain homeostasis, and an increased risk of disease. In this study, a metabolomics approach was used to identify novel metabolic pathways that are perturbed in a mouse model of accelerated aging (SAMP1/kl-/-) an...

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Detalles Bibliográficos
Autores principales: Kim, Soo-A, Lam, Thuy Giang, Yook, Jong-In, Ahn, Sang-Gun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188477/
https://www.ncbi.nlm.nih.gov/pubmed/30222592
http://dx.doi.org/10.18632/aging.101549