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Antioxidant modifications induced by the new metformin derivative HL156A regulate metabolic reprogramming in SAMP1/kl (-/-) mice
Aging is characterized by a reduced ability to defend against stress, an inability to maintain homeostasis, and an increased risk of disease. In this study, a metabolomics approach was used to identify novel metabolic pathways that are perturbed in a mouse model of accelerated aging (SAMP1/kl-/-) an...
Autores principales: | Kim, Soo-A, Lam, Thuy Giang, Yook, Jong-In, Ahn, Sang-Gun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188477/ https://www.ncbi.nlm.nih.gov/pubmed/30222592 http://dx.doi.org/10.18632/aging.101549 |
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