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YKL40 in sporadic amyotrophic lateral sclerosis: cerebrospinal fluid levels as a prognosis marker of disease progression

Amyotrophic lateral sclerosis (ALS) has variable clinical course and fatal outcome. Since inflammation plays a role in the pathogenesis of ALS, chitinase-3-like protein 1 or YKL40 has been assessed as putative biomarker of disease progression. YKL40 mRNA levels are increased in anterior horn of the...

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Detalles Bibliográficos
Autores principales: Andrés-Benito, Pol, Domínguez, Raúl, Colomina, Maria J., Llorens, Franc, Povedano, Mònica, Ferrer, Isidre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188478/
https://www.ncbi.nlm.nih.gov/pubmed/30215603
http://dx.doi.org/10.18632/aging.101551