Sumoylation-deficient Prdx6 repairs aberrant Sumoylation-mediated Sp1 dysregulation-dependent Prdx6 repression and cell injury in aging and oxidative stress

Progressive deterioration of antioxidant response in aging is a major culprit in the initiation of age-related pathobiology induced by oxidative stress. We previously reported that oxidative stress leads to a marked reduction in transcription factor Sp1 and its mediated Prdx6 expression in lens epit...

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Detalles Bibliográficos
Autores principales: Chhunchha, Bhavana, Kubo, Eri, Singh, Prerna, Singh, Dhirendra P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188488/
https://www.ncbi.nlm.nih.gov/pubmed/30215601
http://dx.doi.org/10.18632/aging.101547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188488/
https://www.ncbi.nlm.nih.gov/pubmed/30215601
http://dx.doi.org/10.18632/aging.101547

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