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Mechanistic machine learning: how data assimilation leverages physiologic knowledge using Bayesian inference to forecast the future, infer the present, and phenotype

We introduce data assimilation as a computational method that uses machine learning to combine data with human knowledge in the form of mechanistic models in order to forecast future states, to impute missing data from the past by smoothing, and to infer measurable and unmeasurable quantities that r...

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Detalles Bibliográficos
Autores principales: Albers, David J, Levine, Matthew E, Stuart, Andrew, Mamykina, Lena, Gluckman, Bruce, Hripcsak, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188514/
https://www.ncbi.nlm.nih.gov/pubmed/30312445
http://dx.doi.org/10.1093/jamia/ocy106