Cargando…

KCC2 Regulates Dendritic Spine Formation in a Brain-Region Specific and BDNF Dependent Manner

KCC2 is the major chloride extruder in neurons. The spatiotemporal regulation of KCC2 expression orchestrates the developmental shift towards inhibitory GABAergic drive and the formation of glutamatergic synapses. Whether KCC2’s role in synapse formation is similar in different brain regions is unkn...

Descripción completa

Detalles Bibliográficos
Autores principales: Awad, Patricia Nora, Amegandjin, Clara Akofa, Szczurkowska, Joanna, Carriço, Josianne Nuñes, Fernandes do Nascimento, Antônia Samia, Baho, Elie, Chattopadhyaya, Bidisha, Cancedda, Laura, Carmant, Lionel, Di Cristo, Graziella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188549/
https://www.ncbi.nlm.nih.gov/pubmed/30169756
http://dx.doi.org/10.1093/cercor/bhy198