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KCC2 Regulates Dendritic Spine Formation in a Brain-Region Specific and BDNF Dependent Manner
KCC2 is the major chloride extruder in neurons. The spatiotemporal regulation of KCC2 expression orchestrates the developmental shift towards inhibitory GABAergic drive and the formation of glutamatergic synapses. Whether KCC2’s role in synapse formation is similar in different brain regions is unkn...
Autores principales: | Awad, Patricia Nora, Amegandjin, Clara Akofa, Szczurkowska, Joanna, Carriço, Josianne Nuñes, Fernandes do Nascimento, Antônia Samia, Baho, Elie, Chattopadhyaya, Bidisha, Cancedda, Laura, Carmant, Lionel, Di Cristo, Graziella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188549/ https://www.ncbi.nlm.nih.gov/pubmed/30169756 http://dx.doi.org/10.1093/cercor/bhy198 |
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