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Structure of natural variant transglutaminase 2 reveals molecular basis of gaining stability and higher activity

Multi-functional transglutaminase 2 (TG2), which possesses protein cross-linking and GTP hydrolysis activities, is involved in various cellular processes, including apoptosis, angiogenesis, wound healing, and neuronal regeneration, and is associated with many human diseases, including inflammatory d...

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Detalles Bibliográficos
Autores principales: Ha, Hyun Ji, Kwon, Sunghark, Jeong, Eui Man, Kim, Chang Min, Lee, Ki Baek, Kim, In-Gyu, Park, Hyun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188745/
https://www.ncbi.nlm.nih.gov/pubmed/30321187
http://dx.doi.org/10.1371/journal.pone.0204707