Lyophilized Hybrid Nanostructured Lipid Carriers to Enhance the Cellular Uptake of Verapamil: Statistical Optimization and In Vitro Evaluation

Verapamil is a calcium channel blocker and highly effective in the treatment of hypertension, angina pectoris, and other diseases. However, the drug has a low bioavailability of 20 to 35% due to the first pass effect. The main objective of this study was to develop hybrid verapamil-dextran nanostruc...

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Detalles Bibliográficos
Autores principales: Khan, Arshad Ali, Abdulbaqi, Ibrahim M., Abou Assi, Reem, Murugaiyah, Vikneswaran, Darwis, Yusrida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188975/
https://www.ncbi.nlm.nih.gov/pubmed/30324291
http://dx.doi.org/10.1186/s11671-018-2744-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188975/
https://www.ncbi.nlm.nih.gov/pubmed/30324291
http://dx.doi.org/10.1186/s11671-018-2744-6

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