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Lipopolysaccharide-affinity copolymer senses the rapid motility of swarmer bacteria to trigger antimicrobial drug release

An intelligent drug release system that is triggered into action upon sensing the motion of swarmer P. mirabilis is introduced. The rational design of the drug release system focuses on a pNIPAAm-co-pAEMA copolymer that prevents drug leakage in a tobramycin-loaded mesoporous silica particle by cover...

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Detalles Bibliográficos
Autores principales: Lu, Shengtao, Bi, Wuguo, Du, Quanchao, Sinha, Sheetal, Wu, Xiangyang, Subrata, Arnold, Bhattacharjya, Surajit, Xing, Bengang, Yeow, Edwin K. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189052/
https://www.ncbi.nlm.nih.gov/pubmed/30323232
http://dx.doi.org/10.1038/s41467-018-06729-6