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Plasminogen activation is required for the development of radiation-induced dermatitis

Skin damage caused by radiation therapy (radiodermatitis) is a severe side effect of radiotherapy in cancer patients, and there is currently a lack of effective strategies to prevent or treat such skin damage. In this work, we show with several lines of evidence that plasminogen, a pro-inflammatory...

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Detalles Bibliográficos
Autores principales: Fallah, Mahsa, Shen, Yue, Brodén, Jessica, Bäckman, Assar, Lundskog, Bertil, Johansson, Michael, Blomquist, Michael, Liu, Kui, Wilczynska, Malgorzata, Ny, Tor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189099/
https://www.ncbi.nlm.nih.gov/pubmed/30323258
http://dx.doi.org/10.1038/s41419-018-1106-8